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Human Papillomavirus (HPV) – the main cause of cervical cancer – HPV genotyping

Human Papillomavirus (HPV) - the main cause of cervical cancer – HPV genotyping

HPV (Human papillomavirus) is the most common sexually transmitted infection worldwide. Most women and men, up to 90%, will become infected at some point in their lives. Most infections cause no symptoms and disappear without intervention within 2 years, but certain HPV genotypes can lead to cancer development.

Cervical cancer is the fourth most common cancer in women worldwide, and almost all cases of cervical cancer (99%) are associated with genital HPV infection. HPV virus is also associated with other types of anogenital carcinoma (vulva, vagina, penis, anus), as well as cancer of the mouth, base of the tongue and throat.

There is no specific treatment for the virus itself. However, there are treatments for the changes that HPV can cause, and the HPV vaccine has proven to be an effective prevention and protection system.

Real-Time PCR represents a highly specific (no false positive results) and sensitive (no false negative results) method for testing the presence of different HPV genotypes, enabling early diagnosis of infection, even before the appearance of first symptoms or changes.

HPV Quant 4 (4 HPV virus genotypes) analysis offered by LabMedical laboratory is a molecular test for detection, genotyping and quantification of 4 low and high-risk HPV genotypes using Real-Time PCR method.

High-risk HPV genotypes: 16, 18, which are the most common worldwide and are present in more than 70% of all cervical cancers;

Low-risk HPV genotypes: 6, 11, which cause genital warts (condylomas).

What is the advantage of the HPV (4 genotype) test?

✔ High analytical specificity (no false positives) and sensitivity (no false negatives)

✔ Detection and identification

✔ A single swab enables detection, genotyping and quantification of 4 HPV genotypes

✔ Speed and reliability of results

✔ Molecular test using Real-Time PCR method

✔ Health monitoring

HPV Quant 21 (21 HPV virus genotypes)

HPV (Human papillomavirus) is the most common sexually transmitted infection worldwide. Most women and men, up to 90%, will become infected at some point in their lives. Most infections cause no symptoms and disappear without intervention within 2 years, but certain HPV genotypes can lead to cancer development.

Cervical cancer is the fourth most common cancer in women worldwide, and almost all cases of cervical cancer (99%) are associated with genital HPV infection. HPV virus is also associated with other types of anogenital carcinoma (vulva, vagina, penis, anus), as well as cancer of the mouth, base of the tongue and throat.

There is no specific treatment for the virus itself. However, there are treatments for the changes that HPV can cause, and the HPV vaccine has proven to be an effective prevention and protection system.

Real-Time PCR represents a highly specific (no false positive results) and sensitive (no false negative results) method for testing the presence of different HPV genotypes, enabling early diagnosis of infection, even before the appearance of first symptoms or changes.

HPV (21 genotype) analysis offered by LabMedical laboratory is a molecular test for detection, genotyping and quantification of 21 low and high-risk HPV genotypes using Real-Time PCR method.

High-risk HPV genotypes: 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68, 73 and 82, of which genotypes 16 and 18 are the most common worldwide and are present in more than 70% of all cervical cancers;

Low-risk HPV genotypes: 6, 11, 36, 42, 43, 44, 46, 47 and 50, which cause genital warts (condylomas).

What are the advantages of the HPV (21 genotype) test?

✔ High analytical specificity (no false positives) and sensitivity (no false negatives)

✔ Detection and identification

✔ A single swab enables detection, genotyping and quantification of 21 HPV genotypes

✔ Speed and reliability of results

✔ Molecular test using Real-Time PCR method

✔ Health monitoring

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